SCHEMBL7052950

SCHEMBL7052950

Cl[SiH2]CC1c2ccccc2-c2cccc(C3=CC=CC3)c21

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6657516 0.76 HTR2A (0.30) HTR2A
SCHEMBL9244149 0.76 GPR3 (0.32)
SCHEMBL9659749 0.76 GPR3 (0.32) HTR2A
SCHEMBL6139097 0.75 GPR3 (0.31)
SCHEMBL3900299 0.75 GPR3 (0.31)
SCHEMBL27348447 0.75 HTR2B (0.33)
Hydrochloric Acid SCHEMBL618233 0.74
Bromide SCHEMBL7929245 0.73 GPR3 (0.30)
Hydrochloric Acid SCHEMBL3041072 0.73 GPR3 (0.30)
Hydrochloric Acid SCHEMBL524857 0.73 GPR3 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304319-A2 Metallocenes and processes therefor and therewith Phillips Petroleum Company (US) 2003-04-23 EP disclosed
EP-0628566-B1 Metallocenes and processes therefor and therewith PHILLIPS PETROLEUM CO (US) 2003-03-26 EP disclosed
US-5616752-A CYCLOPENTADIENYL-TYPE SILANE-CONTAINING POLYMERIZATION CATALYSTS PHILLIPS PETROLEUM COMPANY (US) 1997-04-01 US disclosed
US-5565592-A SUPPORTED POLYMERIZATION CATALYSTS FOR OLEFINS COMPRISING ZIRCONIUM OR HAFNIUM AND AN UNSATURATED SILANE ATTACHED TO FLUORENE RINGS PHILLIPS PETROLEUM COMPANY (US) 1996-10-15 US disclosed
US-5466766-A Metallocenes and processes therefor and therewith PHILLIPS PETROLEUM COMPANY (US) 1995-11-14 US disclosed
US-5399636-A Bound to inorganic support, olefin polymerization catalysts PHILLIPS PETROLEUM COMPANY (US) 1995-03-21 US disclosed
EP-0628566-A1 Metallocenes and processes therefor and therewith PHILLIPS PETROLEUM COMPANY (US) 1994-12-14 EP disclosed