Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052594 | 0.81 | MEN1 (0.53) | KMT2AMEN1LMNAMAPK1HTT | |
| SCHEMBL5849656 | 0.79 | KMT2A (0.44) | KMT2AMEN1LMNAMAPK1HTT | |
| SCHEMBL7049798 | 0.78 | MEN1 (0.47) | KMT2AMEN1LMNAHTTMAPT | |
| SCHEMBL7050290 | 0.78 | KDM4E (0.56) | KMT2AMEN1LMNAMAPK1HTT | |
| SCHEMBL7053832 | 0.77 | ALDH1A1 (0.39) | KMT2AMEN1MAPK1HTTMAPT | |
| SCHEMBL7053767 | 0.76 | P2RY12 (0.38) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL7048598 | 0.72 | KMT2A (0.44) | KMT2AMEN1LMNAMAPK1HTT | |
| SCHEMBL7052654 | 0.72 | P2RY12 (0.43) | MEN1 | |
| SCHEMBL7052952 | 0.70 | ALDH1A1 (0.40) | KMT2AMEN1ADRB3LMNAMAPK1 | |
| SCHEMBL7062034 | 0.69 | KMT2A (0.53) | KMT2AMEN1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003022214-A2 | PIPERAZINE AND HOMOPIPERAZINE COMPOUNDS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-03-20 | — | — | WO | disclosed |