Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 17/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052654 | 0.88 | P2RY12 (0.43) | P2RY12MEN1 | |
| SCHEMBL7051730 | 0.88 | P2RY12 (0.38) | P2RY12MEN1HTR6NTSR1KMT2A | |
| SCHEMBL7052594 | 0.86 | MEN1 (0.53) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL7049798 | 0.80 | MEN1 (0.47) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL5848957 | 0.79 | P2RY12 (0.46) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL7049255 | 0.78 | P2RY12 (0.39) | P2RY12MEN1HTR6KMT2A | |
| SCHEMBL7053983 | 0.78 | HTR6 (0.47) | P2RY12MEN1HTR6ALDH1A1KMT2A | |
| SCHEMBL7051550 | 0.77 | P2RY12 (0.39) | P2RY12MEN1HTR6KMT2A | |
| SCHEMBL7050548 | 0.77 | P2RY12 (0.39) | P2RY12MEN1HTR6KMT2A | |
| SCHEMBL7052962 | 0.76 | KMT2A (0.40) | MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003022214-A2 | PIPERAZINE AND HOMOPIPERAZINE COMPOUNDS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-03-20 | — | — | WO | disclosed |