Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CDK9 | P50750 | 9/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7051185 | 0.98 | CYP1A2 (0.46) | CYP1A2CYP2C19CDK9CCNT1CDK1 | |
| SCHEMBL26191686 | 0.83 | ALDH1A1 (0.43) | CYP1A2HTR2CUSP2ALDH1A1CYP2D6 | |
| SCHEMBL1673520 | 0.83 | HTR2C (0.54) | CYP1A2CYP2C19CDK1CDK2SLC6A2 | |
| Hydrochloric Acid SCHEMBL15819292 | 0.81 | HTR2C (0.55) | CYP1A2CYP2C19CDK1CDK2HTR2C | |
| SCHEMBL10820261 | 0.81 | NPC1 (0.43) | SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL71413 | 0.80 | ACKR3 (0.42) | — | |
| SCHEMBL7119762 | 0.78 | CHRM2 (0.42) | CCNT1SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL20817932 | 0.78 | BRD4 (0.46) | CYP1A2CYP2D6 | |
| SCHEMBL5374046 | 0.77 | SLC6A2 (0.54) | CDK9CCNT1SLC6A2SLC6A4HTR2C | |
| SCHEMBL6153952 | 0.76 | DDR1 (0.53) | CDK1CDK2DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030181446-A1 | Novel N-acylated heterocycles | RECORDATI S.A. | 2003-09-25 | — | — | US | disclosed |
| US-20030162777-A1 | Novel N-acylated heterocycles | RECORDATI S.A. | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162777-A1 | Novel N-acylated heterocycles | HTR1A, HTR1D, HTR1E | CYP1A2 578/4885CYP2C19 327/4885CDK9 3203/4885 |
| US-20030181446-A1 | Novel N-acylated heterocycles | HTR1A, HTR1E, HTR2C | CYP1A2 231/4885CYP2C19 94/4885CDK9 1834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.