Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7060002 | 0.80 | MTNR1A (0.32) | MTNR1AMTNR1BRORC | |
| SCHEMBL7060005 | 0.77 | MTNR1A (0.35) | MTNR1AMTNR1BRORC | |
| SCHEMBL8717348 | 0.74 | MPO (0.38) | MTNR1AMTNR1B | |
| SCHEMBL9056237 | 0.73 | MTNR1A (0.34) | MTNR1AMTNR1BRORC | |
| SCHEMBL7055230 | 0.70 | MTNR1A (0.44) | MTNR1AMTNR1BRORC | |
| SCHEMBL7053345 | 0.67 | MTNR1A (0.47) | MTNR1AMTNR1BRORC | |
| SCHEMBL27493167 | 0.65 | MTNR1A (0.45) | MTNR1AMTNR1BRORC | |
| SCHEMBL7053413 | 0.65 | MTNR1A (0.35) | MTNR1AMTNR1B | |
| SCHEMBL7055145 | 0.65 | ACACB (0.35) | MTNR1AMTNR1B | |
| SCHEMBL7050446 | 0.64 | MTNR1A (0.52) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656209-B1 | Melatonin derivatives for use in treating desynchronization disorders | LILLY CO ELI (US) | 2003-05-07 | — | — | EP | disclosed |
| CN-1100533-C | Melatonin derivatives for use in terating desynchronization disorders | LILLY CO ELI (US) | 2003-02-05 | — | — | CN | disclosed |
| CN-1092958-C | Melatonin derivatives for use in treating sleep disorders | LILLY CO ELI (US) | 2002-10-23 | — | — | CN | disclosed |
| EP-0655243-B1 | Melatonin derivatives for use in treating sleep disorders | LILLY CO ELI (US) | 2002-08-21 | — | — | EP | disclosed |
| US-6180657-B1 | SLEEP DISORDERS | ELI LILLY AND COMPANY | 2001-01-30 | — | — | US | disclosed |
| US-5770610-A | ADMINISTERING R-(+)-N-(2-METHYL-2-(5-METHOXY-6-CHLOROINDOL-3-YL)ETHYL) ACETAMIDE | ELI LILLY AND COMPANY (US) | 1998-06-23 | — | — | US | disclosed |
| US-5654325-A | Melatonin derivatives for use in treating sleep disorders | ELI LILLY AND COMPANY (US) | 1997-08-05 | — | — | US | disclosed |
| CN-1107701-A | Melatonin derivatives for use in treating sleep disorders | LILLY CO ELI (US) | 1995-09-06 | — | — | CN | disclosed |
| CN-1107700-A | Melatonin derivatives for use in terating desynchronization disorders | LILLY CO ELI (US) | 1995-09-06 | — | — | CN | disclosed |
| EP-0656209-A2 | Melatonin derivatives for use in treating desynchronization disorders | ELI LILLY AND COMPANY (US) | 1995-06-07 | — | — | EP | disclosed |
| EP-0655243-A2 | Melatonin derivatives for use in treating sleep disorders | ELI LILLY AND COMPANY (US) | 1995-05-31 | — | — | EP | disclosed |
| US-4997845-A | β-alkylmelatonins as ovulation inhibitors | ELI LILLY AND COMPANY (US) | 1991-03-05 | — | — | US | disclosed |