SCHEMBL7053397

SCHEMBL7053397

CCCC(=O)O[SiH](CC)CC

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.59
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
HDAC3 O15379 4/20 0.38
HDAC1 Q13547 4/20 0.38
HDAC2 Q92769 4/20 0.38
HDAC8 Q9BY41 4/20 0.38
FFAR3 O14843 3/20 0.38
TSHR P16473 3/20 0.38
HDAC6 Q9UBN7 1/20 0.33
LMNA P02545 2/20 0.32
DGKA P23743 1/20 0.32
CTSD P07339 1/20 0.32
BCL9 O00512 1/20 0.32
CTNNB1 P35222 1/20 0.32
POLB P06746 1/20 0.31
POLA1 P09884 1/20 0.31
CA12 O43570 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7758098 0.83 ALDH1A1 (0.50) ALDH1A1CES2CES1HDAC3HDAC1
SCHEMBL5074867 0.82 DGKA (0.55) ALDH1A1CES2CES1TSHRLMNA
SCHEMBL5074841 0.82 DGKA (0.55) ALDH1A1CES2CES1TSHRLMNA
SCHEMBL5076554 0.82 DGKA (0.55) ALDH1A1CES2CES1TSHRLMNA
SCHEMBL14312395 0.82 DGKA (0.55) ALDH1A1CES2CES1TSHRLMNA
SCHEMBL5142514 0.82 DGKA (0.55) ALDH1A1CES2CES1TSHRLMNA
SCHEMBL5077113 0.82 DGKA (0.55) ALDH1A1CES2CES1TSHRLMNA
SCHEMBL5077080 0.82 DGKA (0.55) ALDH1A1CES2CES1TSHRLMNA
SCHEMBL3809029 0.79 ALDH1A1 (0.57) ALDH1A1CES2CES1HDAC3HDAC1
SCHEMBL7059562 0.79 ALDH1A1 (0.43) ALDH1A1FFAR3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006118-B1 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond DOW CORNING ASIA LTD (JP) 2003-05-07 EP disclosed
EP-1085022-A1 A method of manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via Si-C- bonds Dow Corning Asia, Ltd. (JP) 2001-03-21 EP disclosed
US-6175031-B1 PLATINUM-CATALYZED HYDROSILYLATION BETWEEN SIH-SUBSTITUTED SILICON COMPOUNDS AND UNSATURATED GROUP-FUNCTIONAL ORGANIC OR ORGANOSILICON COMPOUNDS IN PRESENCE OF A (ACYLOXY)-FUNCTIONAL HYDROGENSILANE COMPOUND OR ACID AND HYDRO(ALKOXY)SILANE DOW CORNING ASIA, LTD. (JP) 2001-01-16 US disclosed
US-6111126-A Method for synthesizing organosilicon compounds that contain a functional group bonded to silicon across the Si-C bond DOW CORNING ASIA, LTD. (JP) 2000-08-29 US disclosed
EP-1006118-A2 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond Dow Corning Asia, Ltd. (JP) 2000-06-07 EP disclosed
US-6060620-A Method for manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via SI--C bonds DOW CORNING ASIA, LTD. (JP) 2000-05-09 US disclosed