Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 7/20 | 0.41 |
| ▸ | DRD1 | P21728 | 7/20 | 0.41 |
| ▸ | DRD4 | P21917 | 7/20 | 0.41 |
| ▸ | DRD5 | P21918 | 7/20 | 0.41 |
| ▸ | DRD3 | P35462 | 7/20 | 0.41 |
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057125 | 0.82 | CCR3 (0.46) | KCNH2MEN1KMT2AMGLLDRD3 | |
| SCHEMBL7053670 | 0.82 | CARM1 (0.43) | KCNH2DRD2PRMT6 | |
| SCHEMBL2967942 | 0.71 | OPRM1 (0.59) | DRD3DRD2 | |
| SCHEMBL28052784 | 0.70 | GRIN2D (0.53) | MEN1KMT2AMGLL | |
| SCHEMBL14143096 | 0.70 | OPRM1 (0.60) | DRD3DRD2 | |
| SCHEMBL3323940 | 0.69 | PRMT6 (0.60) | KCNH2MGLLPRMT6 | |
| SCHEMBL30503933 | 0.69 | OPRM1 (0.51) | MGLLDRD1DRD3DRD2 | |
| SCHEMBL27785492 | 0.68 | GBA1 (0.62) | DRD3DRD2 | |
| SCHEMBL17285992 | 0.68 | CYP1A2 (0.58) | KMT2ADRD3DRD2 | |
| SCHEMBL5888786 | 0.66 | SIGMAR1 (0.75) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |