Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8429705 | 0.83 | ALDH1A1 (0.47) | HPGD | |
| SCHEMBL7056770 | 0.76 | CA1 (0.50) | — | |
| SCHEMBL7690167 | 0.72 | KDM4E (0.46) | KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7050103 | 0.72 | IRAK4 (0.41) | KDM4ESMN1; SMN2 | |
| SCHEMBL7053251 | 0.71 | KDM4E (0.34) | KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL1264053 | 0.71 | ALDH1A1 (0.45) | KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8893668 | 0.67 | CA12 (0.62) | HPGDSMN1; SMN2 | |
| SCHEMBL1705449 | 0.67 | TSHR (0.41) | KDM4EHPGD | |
| SCHEMBL7049447 | 0.67 | ALDH1A1 (0.35) | KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL6205320 | 0.67 | ALDH1A1 (0.52) | KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608070-B1 | Useful for treatment of medical condition in which prostaglandins are implicated as pathogens | NAKAO KAZUNARI (JP) | 2003-08-19 | — | — | US | disclosed |
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |