Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3658983 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL11607317 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL7690167 | 0.82 | KDM4E (0.46) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL482954 | 0.78 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL55705 | 0.78 | ALDH1A1 (0.37) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL8764972 | 0.76 | KDM4E (0.43) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL3015617 | 0.76 | ALDH1A1 (0.35) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL6003548 | 0.76 | DRD1 (0.46) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL7904254 | 0.76 | ALDH1A1 (0.35) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL8764965 | 0.76 | ALOX15 (0.33) | HPGDSMN1; SMN2HTTL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |