Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.69 |
| ▸ | DRD2 | P14416 | 3/20 | 0.65 |
| ▸ | DRD3 | P35462 | 2/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31026378 | 1.00 | HTR1A (0.69) | HTR1ADRD2DRD3HTR2AHTR7 | |
| SCHEMBL21802143 | 0.83 | HTR1A (0.76) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL7057802 | 0.83 | DRD2 (0.61) | HTR1ADRD2DRD3HTR2AHTR7 | |
| SCHEMBL3029003 | 0.82 | HTR1A (1.00) | HTR1AHTR7 | |
| SCHEMBL21802146 | 0.82 | HTR1A (0.74) | HTR1ADRD2DRD3HTR2AHTR7 | |
| SCHEMBL8084154 | 0.81 | HTR1A (1.00) | HTR1AHTR7 | |
| SCHEMBL10835969 | 0.81 | HTR1A (0.76) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL3187453 | 0.80 | DRD3 (0.74) | DRD2DRD3 | |
| SCHEMBL7986148 | 0.80 | HTR1A (1.00) | HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL3207069 | 0.79 | DRD3 (0.72) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221620-A | Benzamide phenylpiperazine radioactive compound and preparation method and application thereof | 中国科学院高能物理研究所 | 2024-06-21 | — | — | CN | disclosed |
| WO-2003028728-A1 | 4-(4-SUBSTITUTED PIPERAZINYL-1YL)-BUTYLCARBOXAMIDES AS D3 DOPAMINE SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |