Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.61 |
| ▸ | DRD3 | P35462 | 3/20 | 0.61 |
| ▸ | HTR1A | P08908 | 8/20 | 0.58 |
| ▸ | HTR7 | P34969 | 5/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053892 | 0.83 | HTR1A (0.69) | DRD2DRD3HTR1AHTR7HTR2A | |
| SCHEMBL31026378 | 0.83 | HTR1A (0.69) | DRD2DRD3HTR1AHTR7HTR2A | |
| SCHEMBL21802017 | 0.83 | HTR7 (0.76) | DRD2DRD3HTR1AHTR7HTR2A | |
| SCHEMBL10836050 | 0.81 | HTR7 (0.72) | DRD2DRD3HTR1AHTR7HTR2A | |
| SCHEMBL7058593 | 0.80 | DRD2 (0.59) | DRD2DRD3HTR7 | |
| SCHEMBL7114350 | 0.80 | ADRA1D (0.44) | DRD2DRD3HTR1AHTR7 | |
| SCHEMBL4684339 | 0.78 | DRD2 (0.64) | DRD2DRD3HTR1AHTR7DRD5 | |
| SCHEMBL4684336 | 0.77 | DRD3 (0.61) | DRD2DRD3HTR1AHTR7HTR2A | |
| SCHEMBL16462988 | 0.76 | DRD2 (1.00) | DRD2DRD3 | |
| SCHEMBL3029003 | 0.75 | HTR1A (1.00) | HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028728-A1 | 4-(4-SUBSTITUTED PIPERAZINYL-1YL)-BUTYLCARBOXAMIDES AS D3 DOPAMINE SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |