Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27937370 | 0.83 | L3MBTL1 (0.47) | L3MBTL1MAPTNPSR1DRD2HTR1A | |
| SCHEMBL27950875 | 0.83 | L3MBTL1 (0.47) | L3MBTL1MAPTNPSR1DRD2HPGD | |
| SCHEMBL27752887 | 0.83 | L3MBTL1 (0.60) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL7058970 | 0.82 | L3MBTL1 (0.44) | L3MBTL1MAPTNPSR1DRD2HTR1A | |
| SCHEMBL28807498 | 0.82 | L3MBTL1 (0.46) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL6268621 | 0.78 | L3MBTL1 (0.66) | L3MBTL1MAPTNPSR1ATMTP53 | |
| SCHEMBL7662939 | 0.78 | L3MBTL1 (0.46) | L3MBTL1MAPTNPSR1DRD2HTR1A | |
| SCHEMBL7690167 | 0.78 | KDM4E (0.46) | L3MBTL1MAPTNPSR1DRD2HPGD | |
| SCHEMBL5090893 | 0.75 | HTR1A (0.67) | L3MBTL1MAPTDRD2HTR1AHPGD | |
| SCHEMBL11404132 | 0.75 | HTR1A (0.43) | L3MBTL1MAPTNPSR1DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |