Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 8/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPRB | P23467 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15576954 | 0.83 | L3MBTL1 (0.66) | L3MBTL1MAPTNPSR1DRD1DRD2 | |
| SCHEMBL7058970 | 0.82 | L3MBTL1 (0.44) | L3MBTL1MAPTNPSR1DRD1DRD2 | |
| SCHEMBL7682354 | 0.81 | DRD1 (0.50) | L3MBTL1MAPTNPSR1DRD1DRD2 | |
| SCHEMBL16920291 | 0.79 | DRD1 (0.45) | L3MBTL1MAPTNPSR1DRD1DRD2 | |
| SCHEMBL15987127 | 0.78 | KDM4E (0.45) | L3MBTL1MAPTNPSR1DRD1DRD2 | |
| SCHEMBL7053895 | 0.78 | L3MBTL1 (0.41) | L3MBTL1MAPTNPSR1DRD1DRD2 | |
| SCHEMBL6268621 | 0.78 | L3MBTL1 (0.66) | L3MBTL1MAPTNPSR1KDM4EATM | |
| SCHEMBL4090048 | 0.78 | L3MBTL1 (0.42) | L3MBTL1MAPTNPSR1DRD1DRD2 | |
| SCHEMBL11217443 | 0.76 | CXCL8 (0.60) | L3MBTL1MAPTKDM4E | |
| SCHEMBL5090893 | 0.75 | HTR1A (0.67) | L3MBTL1MAPTDRD2HTR1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020165232-A1 | Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2002-11-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165232-A1 | Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | CETP, DBI, PLTP | L3MBTL1 2518/4885MAPT 3071/4885NPSR1 2975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.