Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7060766 | 0.94 | MCHR1 (0.40) | NR1H4MCHR1MAPK8MAPK10HPGD | |
| SCHEMBL7054601 | 0.93 | MCHR1 (0.43) | MCHR1EPHX2HPGDMAPTALDH1A1 | |
| SCHEMBL7060834 | 0.91 | MAPT (0.39) | NR1H4MCHR1HPGDMAPTALDH1A1 | |
| SCHEMBL7057769 | 0.91 | EGFR (0.39) | MCHR1HPGDMAPTALDH1A1MEN1 | |
| SCHEMBL7059006 | 0.90 | ALDH1A1 (0.39) | NR1H4MCHR1HPGDMAPTALDH1A1 | |
| SCHEMBL7050099 | 0.90 | ALDH1A1 (0.41) | NR1H4MCHR1HPGDMAPTALDH1A1 | |
| SCHEMBL7058698 | 0.89 | MAPT (0.42) | MAPK10HPGDMAPTALDH1A1MEN1 | |
| SCHEMBL7060964 | 0.88 | ALDH1A1 (0.44) | MCHR1HPGDMAPTALDH1A1MEN1 | |
| SCHEMBL7054997 | 0.88 | ALDH1A1 (0.40) | NR1H4MCHR1HPGDMAPTALDH1A1 | |
| SCHEMBL7057946 | 0.88 | ALDH1A1 (0.40) | MCHR1HPGDMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | claimed |