Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7060834 | 0.94 | MAPT (0.39) | EGFRALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL7059006 | 0.94 | ALDH1A1 (0.39) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL7054601 | 0.92 | MCHR1 (0.43) | EGFRALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL7053934 | 0.91 | NR1H4 (0.40) | EGFRALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL7060964 | 0.91 | ALDH1A1 (0.44) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL7050099 | 0.89 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL6052141 | 0.89 | HTT (0.45) | EGFRERBB2MALT1ALDH1A1HPGD | |
| SCHEMBL7058698 | 0.88 | MAPT (0.42) | EGFRALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL7058692 | 0.88 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL7055517 | 0.88 | ALDH1A1 (0.41) | EGFRERBB2ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | claimed |