Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048692 | 0.84 | NR3C1 (0.61) | KMT2AMEN1GAANR3C1HPGD | |
| SCHEMBL7677676 | 0.83 | NR3C1 (0.51) | KMT2AMEN1GAANR3C1HPGD | |
| SCHEMBL19651843 | 0.81 | MEN1 (0.70) | KMT2AMEN1GAAHPGDL3MBTL1 | |
| SCHEMBL7054408 | 0.76 | NR3C1 (0.50) | KMT2AMEN1NR3C1HPGDLMNA | |
| SCHEMBL7055432 | 0.74 | NR3C1 (0.73) | KMT2AMEN1GAANR3C1HPGD | |
| SCHEMBL7053375 | 0.73 | NR3C1 (0.48) | GAANR3C1LMNANPSR1NPC1 | |
| SCHEMBL19657117 | 0.72 | ALDH1A1 (0.58) | KMT2AMEN1GAATSHRALDH1A1 | |
| SCHEMBL24163473 | 0.71 | MEN1 (0.73) | KMT2AMEN1GAAHPGDL3MBTL1 | |
| SCHEMBL7055363 | 0.70 | NR3C1 (0.50) | GAANR3C1TSHRHTT | |
| SCHEMBL19651827 | 0.67 | HPGD (0.65) | KMT2AMEN1GAAHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102739-B1 | GLUCOCORTICOID AND THYROID HORMONE RECEPTOR LIGANDS FOR THE TREATMENT OF METABOLIC DISORDERS | KAROBIO AB (SE) | 2003-04-23 | — | — | EP | claimed |
| EP-1102739-B1 | GLUCOCORTICOID AND THYROID HORMONE RECEPTOR LIGANDS FOR THE TREATMENT OF METABOLIC DISORDERS | KAROBIO AB (SE) | 2003-04-23 | — | — | EP | disclosed |