Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048773 | 0.86 | DNM1 (0.54) | DNM1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7054663 | 0.83 | DNM1 (0.55) | DNM1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL27593038 | 0.83 | DNM1 (0.55) | DNM1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7111374 | 0.82 | HTT (0.52) | DNM1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7049558 | 0.82 | DNM1 (0.47) | DNM1MEN1KMT2ALMNAGAA | |
| SCHEMBL7053301 | 0.82 | LMNA (0.47) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL27649953 | 0.82 | DNM1 (0.44) | DNM1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7112618 | 0.81 | DNM1 (0.49) | DNM1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7053205 | 0.81 | DNM1 (0.49) | DNM1MEN1KMT2ABCHECHRM2 | |
| SCHEMBL7055848 | 0.81 | DNM1 (0.49) | DNM1MEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |