Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7054551 | 0.82 | TSHR (0.49) | LMNAHPGDKMT2AMEN1TSHR | |
| SCHEMBL5219600 | 0.82 | ANPEP (0.46) | LMNAKMT2AMEN1TDP1ANPEP | |
| SCHEMBL7051118 | 0.75 | OPRD1 (0.47) | LMNAKMT2AMEN1ANPEPALDH1A1 | |
| SCHEMBL3625005 | 0.73 | LMNA (0.71) | LMNAHPGDRAB9AKMT2AMEN1 | |
| SCHEMBL27628350 | 0.73 | LMNA (0.38) | LMNAHPGDRAB9AKMT2AMEN1 | |
| SCHEMBL10403337 | 0.72 | ANPEP (0.53) | LMNAKMT2AMEN1TDP1ANPEP | |
| SCHEMBL6895986 | 0.71 | MEN1 (0.51) | RAB9AKMT2AMEN1TSHRNPC1 | |
| SCHEMBL1848295 | 0.71 | ALDH1A1 (0.49) | LMNAKMT2AMEN1TDP1ANPEP | |
| SCHEMBL27648329 | 0.71 | DNM1 (0.35) | LMNAPOLBANPEPALDH1A1CYP1A2 | |
| SCHEMBL1850858 | 0.71 | ANPEP (0.47) | LMNAKMT2AMEN1TDP1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |