Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1932605 | 0.87 | CNR2 (0.54) | CNR2CNR1C5AR1GLASMN1; SMN2 | |
| SCHEMBL2462475 | 0.86 | CNR2 (0.53) | CNR2CNR1C5AR1GLASMN1; SMN2 | |
| SCHEMBL258729 | 0.85 | C5AR1 (0.64) | CNR2CNR1C5AR1GLASMN1; SMN2 | |
| SCHEMBL1931740 | 0.84 | CNR2 (0.56) | CNR2CNR1C5AR1GLASMN1; SMN2 | |
| SCHEMBL9310747 | 0.83 | CNR2 (0.52) | CNR2GLASMN1; SMN2TAS2R14 | |
| SCHEMBL6900864 | 0.82 | HTT (0.51) | CNR2GLASMN1; SMN2NPSR1HTT | |
| SCHEMBL15943030 | 0.82 | CNR2 (0.52) | CNR2CNR1C5AR1GLASMN1; SMN2 | |
| SCHEMBL15898561 | 0.80 | CNR2 (0.67) | CNR2CNR1C5AR1GLASMN1; SMN2 | |
| SCHEMBL10017634 | 0.78 | CNR2 (0.54) | CNR2CNR1C5AR1GLASMN1; SMN2 | |
| SCHEMBL8491996 | 0.77 | CNR2 (0.44) | CNR2GLAMEN1KMT2ATAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38417-E1 | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2004-02-03 | — | — | US | disclosed |
| US-20020094990-A1 | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives | BERGERON RAYMOND J (US) | 2002-07-18 | — | — | US | disclosed |
| US-6362232-B1 | SKIN DISORERS; INSECTICIDES | BERGERON RAYMOND J (US) | 2002-03-26 | — | — | US | disclosed |
| US-6147262-A | ANTIPROLIFERATIVE AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2000-11-14 | — | — | US | disclosed |
| US-6034139-A | POLYAMINE COMPOUND | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2000-03-07 | — | — | US | disclosed |
| US-5866613-A | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1999-02-02 | — | — | US | disclosed |
| US-5827894-A | ANTITUMOR AGENTS, ANTIGROWTH AGENTS FOR TREATMENT OF PSORIASIS, INSECTICIDES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1998-10-27 | — | — | US | disclosed |
| US-5681837-A | MOSQUITO INSECTICIDAL COMPOSITION | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1997-10-28 | — | — | US | disclosed |
| US-5679682-A | ADMINISTERING SPERMINE DERIVATIVE; MOSQUITO GROWTH CONTROLLER | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1997-10-21 | — | — | US | disclosed |
| US-5455277-A | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5342945-A | Bis-hexahydropyrimidinylakyl compounds | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1994-08-30 | — | — | US | disclosed |
| US-5091576-A | Antipsoriasis, insecticides | UNIVERSITY OF FLORIDA (US) | 1992-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094990-A1 | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives | SRM, SMS, SMOX | CNR2 3306/4885CNR1 3093/4885C5AR1 1111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.