Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055826 | 0.92 | MEN1 (0.48) | MEN1KMT2ASLC1A2TDP1ALDH1A1 | |
| SCHEMBL855064 | 0.87 | MEN1 (0.44) | MEN1KMT2ASLC1A2TDP1ALDH1A1 | |
| SCHEMBL9630466 | 0.85 | MEN1 (0.43) | MEN1KMT2ASLC1A2TDP1ALDH1A1 | |
| SCHEMBL9594621 | 0.82 | TDP1 (0.47) | MEN1KMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL10494506 | 0.80 | MEN1 (0.40) | MEN1KMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL11767007 | 0.80 | TDP1 (0.47) | MEN1KMT2ATDP1ALDH1A1MMP8 | |
| SCHEMBL9321291 | 0.79 | TDP1 (0.45) | MEN1KMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL29870377 | 0.79 | SLC1A2 (0.41) | MEN1KMT2ASLC1A2ALDH1A1TSHR | |
| SCHEMBL7055828 | 0.79 | SLC1A2 (0.38) | MEN1KMT2ASLC1A2TSHR | |
| SCHEMBL19116995 | 0.79 | SLC1A2 (0.38) | MEN1KMT2ASLC1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305407-A2 | PREPARATION OF DICARBOXYLIC ACID MONOESTERS FROM CYANOCARBOXYLIC ACID ESTERS | E. I. du Pont de Nemours and Company (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6455730-B1 | CONTACTING CYANOPROPANOIC ACID METHYL ESTER WITH NITRILASE ISOLATED FROM ACIDOVORAX TO FORM BUTANEDIOIC ACID MONOMETHYL ESTER WITH NO PRODUCTION OF CYANOPROPIONIC ACID OR BUTANEDIOIC ACID | E. I. DU PONT DE NEMOURS & COMPANY | 2002-09-24 | — | — | US | disclosed |
| WO-2002012527-A2 | PREPARATION OF DICARBOXYLIC ACID MONOESTERS FROM CYANOCARBOXYLIC ACID ESTERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-02-14 | — | — | WO | disclosed |