Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10925106 | 0.92 | MAPT (0.35) | SLC1A2MAPTTSHRMEN1KMT2A | |
| SCHEMBL10365590 | 0.83 | MAPT (0.38) | MAPT | |
| SCHEMBL8846572 | 0.81 | TSHR (0.35) | SLC1A2MAPTTSHRMEN1KMT2A | |
| SCHEMBL335124 | 0.80 | CHRM1 (0.41) | SLC1A2MAPTFAAH | |
| SCHEMBL7055006 | 0.79 | MEN1 (0.46) | SLC1A2TSHRMEN1KMT2A | |
| SCHEMBL334795 | 0.78 | MAPT (0.44) | SLC1A2MAPTTSHRMEN1KMT2A | |
| SCHEMBL7056636 | 0.77 | CYP1A2 (0.45) | SLC1A2MAPT | |
| SCHEMBL6910766 | 0.77 | CA2 (0.47) | SLC1A2MAPTTSHRFAAH | |
| SCHEMBL335608 | 0.77 | MAPT (0.41) | SLC1A2MAPTMEN1KMT2A | |
| SCHEMBL3003297 | 0.77 | MAPT (0.36) | MAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920104-A | Preparation method for green synthesis of N-acetyl-5-methoxytryptamine | 福建科宏生物工程股份有限公司 | 2021-06-08 | — | — | CN | disclosed |
| EP-1305407-A2 | PREPARATION OF DICARBOXYLIC ACID MONOESTERS FROM CYANOCARBOXYLIC ACID ESTERS | E. I. du Pont de Nemours and Company (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6455730-B1 | CONTACTING CYANOPROPANOIC ACID METHYL ESTER WITH NITRILASE ISOLATED FROM ACIDOVORAX TO FORM BUTANEDIOIC ACID MONOMETHYL ESTER WITH NO PRODUCTION OF CYANOPROPIONIC ACID OR BUTANEDIOIC ACID | E. I. DU PONT DE NEMOURS & COMPANY | 2002-09-24 | — | — | US | disclosed |
| WO-2002012527-A2 | PREPARATION OF DICARBOXYLIC ACID MONOESTERS FROM CYANOCARBOXYLIC ACID ESTERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-02-14 | — | — | WO | disclosed |
| EP-0112142-B1 | PYRIDINE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-06-20 | — | — | EP | disclosed |
| US-4931591-A | Novel 5-amino-4-hydroxyvaleryl derivatives | CIBA-GEIGY CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
| US-4863936-A | 3,5-Substituted-2-pyridyl-alkylaminocyclobutenediones having histamine h1 -antagonist activity | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-09-05 | — | — | US | disclosed |
| US-4727060-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| EP-0134091-B1 | PYRIMIDONE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-06-16 | — | — | EP | disclosed |
| US-4665078-A | RHINITIS, HAY FEVER, ASTHMA, ECZEMA | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-05-12 | — | — | US | disclosed |
| EP-0013071-A1 | Pyrimidinone derivatives, processes for preparing them and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-07-09 | — | — | EP | disclosed |
| US-4210652-A | INHIBITORS OF H-2 HISTAMINE RECEPTORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-07-01 | — | — | US | disclosed |
| WO-1980000966-A1 | NEW HISTAMINE H2-ANTAGONISTS | SMITH KLINE FRENCH LAB (GB) | 1980-05-15 | — | — | WO | disclosed |
| US-4189488-A | ANTIHISTAMINES AND GASTRIC ANTISECRETORY AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-02-19 | — | — | US | disclosed |
| US-4185103-A | ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-01-22 | — | — | US | disclosed |
| US-4156727-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-05-29 | — | — | US | disclosed |
| US-4154838-A | ANTIHISTAMINE | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-05-15 | — | — | US | disclosed |
| US-4154834-A | HETEROCYCLIC-(THIO)ALKYLAMINO SUBSTITUTED-4-PYRIMIDONE OR -THIONES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-05-15 | — | — | US | disclosed |
| US-4139624-A | INHIBITORS OF H-2 HISTAMINE RECEPTORS | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-02-13 | — | — | US | disclosed |
| US-4118502-A | ANTIHISTAMINE | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1978-10-03 | — | — | US | disclosed |