Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055006 | 0.92 | MEN1 (0.46) | MEN1KMT2ATDP1TSHRALDH1A1 | |
| SCHEMBL855064 | 0.90 | MEN1 (0.44) | MEN1KMT2ATDP1TSHRALDH1A1 | |
| SCHEMBL9594621 | 0.90 | TDP1 (0.47) | MEN1KMT2ATDP1TSHRALDH1A1 | |
| SCHEMBL9630466 | 0.89 | MEN1 (0.43) | MEN1KMT2ATDP1TSHRALDH1A1 | |
| SCHEMBL9321291 | 0.86 | TDP1 (0.45) | MEN1KMT2ATDP1TSHRALDH1A1 | |
| SCHEMBL21485102 | 0.85 | NAAA (0.42) | MEN1KMT2ATDP1TSHRMAPK1 | |
| SCHEMBL21480847 | 0.85 | NAAA (0.42) | MEN1KMT2ATDP1TSHRMAPK1 | |
| SCHEMBL19105381 | 0.84 | TSHR (0.38) | MEN1KMT2ATDP1TSHRALDH1A1 | |
| SCHEMBL14353237 | 0.82 | KMT2A (0.47) | MEN1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL1260192 | 0.82 | MEN1 (0.47) | MEN1KMT2ATSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798116-A | Method for improving conversion rate of diethyl 2-cyanoethyl malonate | 福建科宏生物工程股份有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-115010623-A | Preparation method of 2-cyanoethyl diethyl malonate | 福建科宏生物工程股份有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-113786779-A | Melatonin hydrogenation production equipment and preparation process thereof | 山东巨能药业有限公司 | 2021-12-14 | — | — | CN | claimed |
| CN-108484484-B | Preparation method of 2-oxo-3-ethyl piperidinecarboxylate | 上海泾维化工科技有限公司 | 2021-01-05 | — | — | CN | claimed |
| CN-108484484-A | The preparation method of 2- oxygen-ethyl nipecotate | 上海泾维化工科技有限公司 | 2018-09-04 | — | — | CN | claimed |
| JP-6107618-A | — | — | None | — | — | JP | disclosed |
| US-12637680-B2 | Recombinant host cells for the production of malonate | LYGOS, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| CN-119798116-A | Method for improving conversion rate of diethyl 2-cyanoethyl malonate | 福建科宏生物工程股份有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-119709450-A | Recombinant host cells for malonate production | 利戈斯股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| US-12221524-B2 | Polymerization initiator, curable composition, dental material, and preparation kit for curable composition | MITSUI CHEMICALS, INC. (JP) | 2025-02-11 | — | — | US | disclosed |
| CN-114616330-B | Recombinant host cells for malonate production | 利戈斯股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| US-20240191216-A1 | RECOMBINANT HOST CELLS FOR THE PRODUCTION OF MALONATE | LYGOS, INC. (US) | 2024-06-13 | — | — | US | disclosed |
| WO-1980000966-A1 | NEW HISTAMINE H2-ANTAGONISTS | SMITH KLINE FRENCH LAB (GB) | 1980-05-15 | — | — | WO | disclosed |
| US-4189488-A | ANTIHISTAMINES AND GASTRIC ANTISECRETORY AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-02-19 | — | — | US | disclosed |
| US-4185103-A | ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-01-22 | — | — | US | disclosed |
| US-4156727-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-05-29 | — | — | US | disclosed |
| US-4154838-A | ANTIHISTAMINE | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-05-15 | — | — | US | disclosed |
| US-4154834-A | HETEROCYCLIC-(THIO)ALKYLAMINO SUBSTITUTED-4-PYRIMIDONE OR -THIONES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-05-15 | — | — | US | disclosed |
| US-4139624-A | INHIBITORS OF H-2 HISTAMINE RECEPTORS | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-02-13 | — | — | US | disclosed |
| US-4118502-A | ANTIHISTAMINE | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1978-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12637680-B2 | Recombinant host cells for the production of malonate | DCXR, ETV1, LYPLA2 | MEN1 4165/4885KMT2A 361/4885TDP1 3582/4885 |
| US-20240191216-A1 | RECOMBINANT HOST CELLS FOR THE PRODUCTION OF MALONATE | ME1, MAL2, ME3 | MEN1 1464/4885KMT2A 4341/4885TDP1 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.