SCHEMBL7055192

SCHEMBL7055192

C[SiH](C)C1=C(c2cccc3c2Cc2ccccc2-3)C=CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.40
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HTR2B P41595 2/20 0.33
HTR7 P34969 1/20 0.33
PGR P06401 1/20 0.32
MAP3K9 P80192 1/20 0.31
MAP3K11 Q16584 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
DRD2 P14416 1/20 0.30
DRD4 P21917 1/20 0.30
DRD3 P35462 1/20 0.30
MAOA P21397 2/20 0.30
CYP1A2 P05177 1/20 0.30
ADRA2A P08913 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2C P28335 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8677895 0.80 PNMT (0.42) PNMTNPC1RAB9AHTR2BHTR7
Hydrochloric Acid SCHEMBL3679753 0.78 PNMT (0.36) PNMTNPC1RAB9AHTR2BHTR7
SCHEMBL8369890 0.78 PNMT (0.41) PNMTNPC1RAB9AHTR2BHTR7
Hydrochloric Acid SCHEMBL7938769 0.78 PNMT (0.41) PNMTNPC1RAB9AHTR2BHTR7
Chloromethane SCHEMBL3685930 0.77 PNMT (0.35) PNMTNPC1RAB9AHTR2BHTR7
Hydrochloric Acid SCHEMBL8469546 0.76 PNMT (0.41) PNMTNPC1RAB9AHTR2BHTR7
SCHEMBL30103334 0.73 PNMT (0.63) PNMTNPC1RAB9AHTR2BHTR7
SCHEMBL524602 0.73 PNMT (0.63) PNMTNPC1RAB9AHTR2BHTR7
SCHEMBL7052931 0.72 PNMT (0.39) PNMTNPC1RAB9AHTR2BHTR7
Chloromethane SCHEMBL3685925 0.72 PNMT (0.36) PNMTNPC1RAB9AHTR2BHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985674-B1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS MITSUBISHI CHEM CORP (JP) 2003-04-23 EP disclosed
US-6255515-B1 COORDINATION POLYMERIZATION CATALYSTS MITSUBISHI CHEMICAL CORPORATION (JP) 2001-07-03 US disclosed