SCHEMBL7052931

SCHEMBL7052931

CC1=CCC([SiH](C)C)=C1c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
PGR P06401 1/20 0.36
HTR7 P34969 1/20 0.33
HTR2B P41595 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7057184 0.82 PNMT (0.36) PNMTNPC1RAB9AHTR7HTR2B
Hydrochloric Acid SCHEMBL3355751 0.73 PNMT (0.38) PNMTNPC1RAB9APGRHTR7
Hydrochloric Acid SCHEMBL8856830 0.73 PNMT (0.38) PNMTNPC1RAB9APGRHTR7
SCHEMBL7055192 0.72 PNMT (0.40) PNMTNPC1RAB9APGRHTR7
SCHEMBL524602 0.72 PNMT (0.63) PNMTNPC1RAB9APGRHTR7
SCHEMBL30103334 0.72 PNMT (0.63) PNMTNPC1RAB9APGRHTR7
SCHEMBL2877998 0.70 PNMT (0.61) PNMTNPC1RAB9APGRHTR7
SCHEMBL8468716 0.70 PNMT (0.49) PNMTNPC1RAB9APGRHTR7
SCHEMBL1480277 0.69 PNMT (0.52) PNMTNPC1RAB9APGRHTR7
SCHEMBL8369890 0.68 PNMT (0.41) PNMTNPC1RAB9APGRHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985674-B1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS MITSUBISHI CHEM CORP (JP) 2003-04-23 EP disclosed
US-6255515-B1 COORDINATION POLYMERIZATION CATALYSTS MITSUBISHI CHEMICAL CORPORATION (JP) 2001-07-03 US disclosed
EP-0985674-A1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS MITSUBISHI CHEMICAL CORPORATION (JP) 2000-03-15 EP disclosed