Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 12/20 | 0.57 |
| ▸ | DRD2 | P14416 | 10/20 | 0.57 |
| ▸ | HTR2A | P28223 | 5/20 | 0.57 |
| ▸ | HTR2C | P28335 | 4/20 | 0.57 |
| ▸ | HTR1A | P08908 | 4/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | PLD1 | Q13393 | 4/20 | 0.49 |
| ▸ | PLD2 | O14939 | 3/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7054406 | 0.85 | DRD3 (0.57) | DRD3DRD2HTR2AHTR2CHTR1A | |
| SCHEMBL7057298 | 0.85 | DRD2 (0.57) | DRD3DRD2HTR2AHTR2CHTR1A | |
| SCHEMBL7058761 | 0.82 | DRD2 (0.53) | DRD3DRD2HTR2AHTR2CHTR1A | |
| SCHEMBL7050625 | 0.82 | DRD2 (0.54) | DRD3DRD2HTR2AHTR2CHTR1A | |
| SCHEMBL7115347 | 0.77 | DRD3 (0.49) | DRD3DRD2HTR2AHTR2CHTR1A | |
| SCHEMBL4521349 | 0.75 | DRD3 (0.73) | DRD3DRD2HTR2AHTR2CHTR1A | |
| SCHEMBL7059254 | 0.74 | DRD3 (0.65) | DRD3DRD2HTR2AHTR2CHTR1A | |
| SCHEMBL7057584 | 0.73 | DRD3 (0.69) | DRD3DRD2ADRA1A | |
| SCHEMBL5540260 | 0.72 | TP53 (0.51) | DRD2HTR1AHRH1 | |
| SCHEMBL4533987 | 0.72 | SLC6A4 (0.72) | DRD3DRD2HTR2AHTR2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |