Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 14/20 | 0.69 |
| ▸ | DRD2 | P14416 | 13/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 9/20 | 0.69 |
| ▸ | DRD4 | P21917 | 5/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119593 | 0.90 | CCR3 (0.55) | DRD3DRD2ADRA1A | |
| SCHEMBL7060979 | 0.88 | DRD2 (0.52) | DRD3DRD2ADRA1ADRD4 | |
| SCHEMBL7054406 | 0.88 | DRD3 (0.57) | DRD3DRD2ADRA1ADRD4 | |
| Hydrochloric Acid SCHEMBL7058141 | 0.87 | DRD2 (0.53) | DRD3DRD2ADRA1ADRD4 | |
| SCHEMBL7055659 | 0.86 | DRD2 (0.50) | DRD3DRD2ADRA1A | |
| Hydrochloric Acid SCHEMBL7056135 | 0.85 | DRD4 (0.59) | DRD3DRD2ADRA1ADRD4SLC6A4 | |
| SCHEMBL7057796 | 0.84 | DRD3 (0.71) | DRD3DRD2ADRA1ADRD4SLC6A2 | |
| SCHEMBL7052435 | 0.83 | DRD2 (0.48) | DRD3DRD2ADRA1ADRD4 | |
| SCHEMBL7052427 | 0.83 | DRD2 (0.48) | DRD3DRD2ADRA1A | |
| SCHEMBL7058078 | 0.81 | DRD2 (0.56) | DRD3DRD2ADRA1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |