Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 10/20 | 0.49 |
| ▸ | DRD2 | P14416 | 9/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053088 | 0.86 | DRD3 (0.49) | DRD3DRD2ADRA1ACHRM4TP53 | |
| Hydrochloric Acid SCHEMBL7059854 | 0.86 | CCR3 (0.51) | DRD3DRD2ADRA1ACHRM4DRD4 | |
| SCHEMBL7050625 | 0.81 | DRD2 (0.54) | DRD3DRD2ADRA1ALMNAOPRM1 | |
| SCHEMBL7056847 | 0.78 | DRD2 (0.49) | DRD3DRD2ADRA1ATP53HTR1A | |
| SCHEMBL7119545 | 0.77 | DRD3 (0.64) | DRD3DRD2ADRA1AHTR1ADRD4 | |
| SCHEMBL7055320 | 0.77 | DRD3 (0.57) | DRD3DRD2ADRA1ASLC5A7HTR1A | |
| SCHEMBL7118079 | 0.76 | DRD2 (0.46) | DRD3DRD2TP53HTR1ADRD4 | |
| SCHEMBL7051851 | 0.76 | DRD3 (0.49) | DRD3DRD2TP53DRD4HTR2A | |
| SCHEMBL7056494 | 0.75 | DRD2 (0.60) | DRD3DRD2ADRA1ATP53HTR1A | |
| SCHEMBL7058078 | 0.75 | DRD2 (0.56) | DRD3DRD2ADRA1ACHRM4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |