Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 15/20 | 0.50 |
| ▸ | THRA | P10827 | 11/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055355 | 0.89 | THRB (0.47) | THRBTHRAEP300GAATDP1 | |
| SCHEMBL7034348 | 0.85 | THRA (0.58) | THRBTHRAGAA | |
| SCHEMBL7058733 | 0.83 | THRB (0.59) | THRBTHRA | |
| SCHEMBL11508744 | 0.75 | SMN1; SMN2 (0.56) | EP300GAAL3MBTL1ALDH1A1 | |
| SCHEMBL7055219 | 0.74 | KCNQ2 (0.46) | THRBTHRATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL13412598 | 0.74 | GAA (0.74) | EP300GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL13412596 | 0.74 | GAA (0.74) | EP300GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL13412597 | 0.74 | GAA (0.74) | EP300GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL13412605 | 0.74 | GAA (0.74) | EP300GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL13412593 | 0.74 | GAA (0.74) | EP300GAATDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307426-A1 | AMINO DIPHENYL ETHERS AND AMIDO DIPHENYL ETHERS | Bayer Aktiengesellschaft (DE) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002012169-A1 | AMINO DIPHENYL ETHERS AND AMIDO DIPHENYL ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-02-14 | — | — | WO | disclosed |