Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 15/20 | 0.59 |
| ▸ | THRA | P10827 | 11/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024880 | 0.87 | THRB (0.57) | THRBTHRAALOX15MAPK1POLB | |
| SCHEMBL7055352 | 0.83 | THRB (0.50) | THRBTHRA | |
| SCHEMBL2785263 | 0.79 | THRB (0.64) | THRBTHRAALOX15MAPK1 | |
| SCHEMBL12312631 | 0.78 | THRB (0.56) | THRBTHRAALOX15MAPK1 | |
| SCHEMBL7055219 | 0.77 | KCNQ2 (0.46) | THRBTHRA | |
| SCHEMBL23172131 | 0.76 | RAB9A (0.73) | ALOX15MAPK1POLBHDAC1HCAR2 | |
| SCHEMBL5396284 | 0.74 | THRB (1.00) | THRBTHRA | |
| SCHEMBL7060025 | 0.73 | THRB (0.55) | THRBTHRA | |
| SCHEMBL7055355 | 0.72 | THRB (0.47) | THRBTHRAPOLB | |
| SCHEMBL5393816 | 0.71 | THRB (0.85) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307426-A1 | AMINO DIPHENYL ETHERS AND AMIDO DIPHENYL ETHERS | Bayer Aktiengesellschaft (DE) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002012169-A1 | AMINO DIPHENYL ETHERS AND AMIDO DIPHENYL ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-02-14 | — | — | WO | disclosed |