Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1418030 | 1.00 | CES2 (0.54) | CES2CYP1A2ALDH1A1MGLLLMNA | |
| SCHEMBL3134710 | 0.85 | ALDH1A1 (0.57) | CYP1A2ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL7789901 | 0.79 | TP53 (0.55) | CES2ALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL735945 | 0.79 | ATM (0.59) | CES2ALDH1A1SMN1; SMN2HTTTRPM8 | |
| SCHEMBL7695 | 0.78 | ALDH1A1 (0.47) | CYP1A2ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL27539931 | 0.76 | ALDH1A1 (0.51) | CES2CYP1A2ALDH1A1MGLLSMN1; SMN2 | |
| Benzene SCHEMBL10436420 | 0.74 | CES2 (0.69) | CES2CYP1A2ALDH1A1LMNASMN1; SMN2 | |
| Benzene SCHEMBL10436419 | 0.74 | CES2 (0.69) | CES2CYP1A2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6170071 | 0.73 | ALDH1A1 (0.61) | CYP1A2ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL10530983 | 0.73 | ALDH1A1 (0.57) | CES2ALDH1A1SMN1; SMN2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971915-B1 | METHOD FOR PREPARING 2-THIENYLETHYLAMINE DERIVATIVES | SANOFI SYNTHELABO (FR) | 2003-05-14 | — | — | EP | disclosed |
| US-6080875-A | REACTING A THIENYLGLYCIDIC DERIVATIVE WITH A PHENYLGLYCINE ESTER IN THE PRESENCE OF AN ALKALI METAL BOROHYDRIDE, DECYCLIZATION; PREPARING DRUGS FOR TREATING ANTI-PLATELET AGGREGATION AND ANTITHROMBOTIC ACTIVITIES | SANOFI-SYNTHELABO (FR) | 2000-06-27 | — | — | US | disclosed |
| EP-0971915-A1 | METHOD FOR PREPARING 2-THIENYLETHYLAMINE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998039322-A1 | METHOD FOR PREPARING 2-THIENYLETHYLAMINE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 1998-09-11 | — | — | WO | disclosed |