Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12754892 | 0.83 | TSHR (0.45) | RAB9AMEN1KMT2ALMNANPC1 | |
| SCHEMBL29695082 | 0.80 | — | — | |
| SCHEMBL1445568 | 0.80 | — | — | |
| SCHEMBL30196047 | 0.80 | SMN1; SMN2 (0.43) | RAB9AMEN1KMT2ALMNANPC1 | |
| SCHEMBL19732855 | 0.78 | KDM4E (0.47) | L3MBTL1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL8241004 | 0.78 | NPC1 (0.49) | L3MBTL1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL5700264 | 0.76 | CYP2C9 (0.50) | RAB9AMEN1KMT2ALMNANPC1 | |
| SCHEMBL27863637 | 0.75 | SLC6A2 (0.50) | L3MBTL1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL30196076 | 0.75 | SLC6A2 (0.50) | L3MBTL1RAB9AMEN1KMT2ALMNA | |
| Cyanide SCHEMBL28048133 | 0.75 | NFE2L2 (0.46) | L3MBTL1RAB9AMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |