Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052387 | 0.85 | CYP19A1 (0.47) | SCN9ACYP11B2CYP19A1CYP11B1HRH4 | |
| Hydrochloric Acid SCHEMBL4599477 | 0.84 | CYP19A1 (0.46) | SCN9ACYP11B2CYP19A1CYP11B1HRH4 | |
| SCHEMBL7056102 | 0.78 | PDK2 (0.43) | SCN9ACYP11B2CYP19A1CYP11B1HRH4 | |
| SCHEMBL1038946 | 0.78 | HRH4 (0.41) | KIF11TRPA1SCN5ASCN9AHRH4 | |
| SCHEMBL20930502 | 0.76 | PDK2 (0.36) | KIF11TRPA1SCN5ASCN9AKDM1A | |
| SCHEMBL4599915 | 0.75 | FFAR4 (0.50) | KIF11TRPA1SCN5ASCN9ACYP11B2 | |
| SCHEMBL22242509 | 0.75 | PDK2 (0.35) | KIF11TRPA1SCN5ASCN9AKDM1A | |
| SCHEMBL17630052 | 0.74 | PDE3B (0.46) | KIF11KDM1AMAOBCYP11B2CYP11B1 | |
| SCHEMBL8119291 | 0.74 | EPAS1 (0.43) | KIF11TRPA1SCN5ASCN9AHRH4 | |
| SCHEMBL22816019 | 0.74 | IDH1 (0.39) | MAOBHRH4MAOAPTGDR2PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030181446-A1 | Novel N-acylated heterocycles | RECORDATI S.A. | 2003-09-25 | — | — | US | disclosed |
| US-20030162777-A1 | Novel N-acylated heterocycles | RECORDATI S.A. | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162777-A1 | Novel N-acylated heterocycles | HTR1A, HTR1D, HTR1E | KIF11 2902/4885TRPA1 212/4885SCN5A 192/4885 |
| US-20030181446-A1 | Novel N-acylated heterocycles | HTR1A, HTR1E, HTR2C | KIF11 3969/4885TRPA1 294/4885SCN5A 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.