Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29074269 | 0.77 | PTGDR2 (0.42) | ANO1GCGRPTGDR2LMNAMAPT | |
| SCHEMBL31342467 | 0.75 | NOTUM (0.43) | IDH1PDE3AMAOAMAOBSLC6A4 | |
| SCHEMBL1416864 | 0.75 | NOTUM (0.43) | IDH1PDE3AMAOAMAOBSLC6A4 | |
| SCHEMBL22816255 | 0.74 | MARS1 (0.45) | GCGRMAPT | |
| SCHEMBL7056110 | 0.74 | KIF11 (0.38) | PDE3BPDE3APTGDR2MAOAMAOB | |
| SCHEMBL30010427 | 0.73 | MAOA (0.43) | IDH1MAOAMAOBSLC6A4ALPL | |
| SCHEMBL1337181 | 0.73 | MAOA (0.43) | IDH1MAOAMAOBSLC6A4ALPL | |
| SCHEMBL4704298 | 0.73 | MAPK1 (0.43) | MAOAMAOBLMNAMAPTHPGD | |
| SCHEMBL2414604 | 0.72 | SLC1A5 (0.43) | KMT2AGRIN2B | |
| SCHEMBL29855159 | 0.72 | SLC1A5 (0.43) | KMT2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |