Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13273862 | 0.83 | MAPT (0.63) | TP53MAPTPOLBL3MBTL1LMNA | |
| SCHEMBL8268112 | 0.81 | MAPT (0.60) | TP53MAPTPOLBL3MBTL1LMNA | |
| SCHEMBL11371482 | 0.79 | MAPT (0.62) | TP53MAPTPOLBL3MBTL1LMNA | |
| SCHEMBL6995077 | 0.78 | L3MBTL1 (0.56) | TP53MAPTPOLBL3MBTL1LMNA | |
| SCHEMBL1824204 | 0.77 | PARP1 (0.49) | TP53MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8311929 | 0.77 | L3MBTL1 (0.72) | TP53MAPTPOLBL3MBTL1LMNA | |
| SCHEMBL20867570 | 0.75 | TP53 (0.63) | TP53MAPTPOLBLMNASMN1; SMN2 | |
| SCHEMBL19287155 | 0.75 | L3MBTL1 (0.64) | TP53MAPTPOLBL3MBTL1LMNA | |
| SCHEMBL13130238 | 0.74 | L3MBTL1 (1.00) | TP53MAPTPOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL7083964 | 0.74 | MAPT (0.53) | TP53MAPTPOLBL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030166694-A1 | Glycinamides | MERCK PATENT GMBH (DE) | 2003-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166694-A1 | Glycinamides | F11, SERPINC1, F13A1 | TP53 4799/4885MAPT 4813/4885POLB 4699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.