Lenabasum

Lenabasum

SCHEMBL7056887

CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C(=O)O)CC21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 14/20 1.00
CNR1 P21554 13/20 1.00
GLRA1 P23415 1/20 0.74
NR1I2 O75469 1/20 0.67
ADORA3 P0DMS8 1/20 0.67
SLC6A3 Q01959 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lenabasum SCHEMBL29872156 1.00 CNR2 (1.00) CNR2CNR1GLRA1NR1I2ADORA3
Lenabasum SCHEMBL26441 1.00 CNR2 (1.00) CNR2CNR1GLRA1NR1I2ADORA3
Lenabasum SCHEMBL7056881 1.00 CNR2 (1.00) CNR2CNR1GLRA1NR1I2ADORA3
SCHEMBL17414503 1.00 CNR2 (1.00) CNR2CNR1GLRA1NR1I2ADORA3
SCHEMBL13035015 1.00 CNR2 (1.00) CNR2CNR1GLRA1NR1I2ADORA3
Lenabasum SCHEMBL23202520 1.00 CNR2 (1.00) CNR2CNR1GLRA1NR1I2ADORA3
Lenabasum SCHEMBL29362927 1.00 CNR2 (1.00) CNR2CNR1GLRA1NR1I2ADORA3
Lenabasum SCHEMBL6406468 1.00 CNR2 (1.00) CNR2CNR1GLRA1NR1I2ADORA3
SCHEMBL29611496 0.99 CNR2 (0.98) CNR2CNR1GLRA1NR1I2ADORA3
SCHEMBL14501182 0.99 CNR2 (0.98) CNR2CNR1GLRA1NR1I2ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040063697-A1 Compositions of cyclooxygenase-2 selective inhibitors and thrombolytic agents for the treatment or prevention of a vaso-occlusive event PHARMACIA CORPORATION 2004-04-01 US claimed
WO-2017133517-A1 PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF 四川海思科制药有限公司 2017-08-10 WO disclosed
US-8637087-B2 Treatment of interstitial cystitis using (6aR, 10aR)-Δ8-tetrahydrocannabinol-11-OIC acids JB THERAPEUTICS INC. (US) 2014-01-28 US disclosed
US-20110318425-A1 TREATMENT OF INTERSTITIAL CYSTITIS USING (6aR, 10aR)- DELTA-8-TETRAHDRAOCANNABINOL-11-OIC ACIDS CORBUS PHARMACEUTICALS INC. 2011-12-29 US disclosed
US-20080182892-A1 Treatment of interstitial cystitis using (6aR, 10aR)-delta-8-tetrahydrocannabinol-11-oic acids INDEVUS PHARMACEUTICALS, INC. (US) 2008-07-31 US disclosed
US-20040063697-A1 Compositions of cyclooxygenase-2 selective inhibitors and thrombolytic agents for the treatment or prevention of a vaso-occlusive event PHARMACIA CORPORATION 2004-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063697-A1 Compositions of cyclooxygenase-2 selective inhibitors and thrombolytic agents for the treatment or prevention of a vaso-occlusive event PTGIS, PTGIR, PTGS2 CNR2 328/4885CNR1 1000/4885GLRA1 2551/4885
US-20080182892-A1 Treatment of interstitial cystitis using (6aR, 10aR)-delta-8-tetrahydrocannabinol-11-oic acids CNR1, CNR2, GPR18 CNR2 2/4885CNR1 1/4885GLRA1 305/4885
US-20110318425-A1 TREATMENT OF INTERSTITIAL CYSTITIS USING (6aR, 10aR)- DELTA-8-TETRAHDRAOCANNABINOL-11-OIC ACIDS CNR1, CNR2, CYSLTR1 CNR2 2/4885CNR1 1/4885GLRA1 362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.