Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | USP14 | P54578 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057215 | 1.00 | ALDH1A1 (0.41) | ALDH1A1HTTKDM4ESMN1; SMN2APOBEC3A | |
| SCHEMBL7054419 | 0.83 | ALDH1A1 (0.60) | ALDH1A1HTTKDM4ESMN1; SMN2APOBEC3A | |
| SCHEMBL7054422 | 0.83 | ALDH1A1 (0.60) | ALDH1A1HTTKDM4ESMN1; SMN2APOBEC3A | |
| SCHEMBL7058008 | 0.80 | TSHR (0.47) | ALDH1A1HTTKDM4ESMN1; SMN2MAPT | |
| SCHEMBL7058013 | 0.80 | TSHR (0.47) | ALDH1A1HTTKDM4ESMN1; SMN2MAPT | |
| SCHEMBL7052338 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HTTKDM4ESMN1; SMN2APOBEC3A | |
| SCHEMBL7052334 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HTTKDM4ESMN1; SMN2APOBEC3A | |
| SCHEMBL6642453 | 0.77 | TDP1 (0.41) | ALDH1A1KDM4ESMN1; SMN2MAPTGAA | |
| SCHEMBL303938 | 0.74 | KDM4E (0.40) | ALDH1A1KDM4ESMN1; SMN2MAPTGAA | |
| SCHEMBL7058622 | 0.72 | MEN1 (0.54) | ALDH1A1MAPTGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608196-B2 | Structurally diverse; parallel approach | GALILEO PHARMACEUTICALS, INC. | 2003-08-19 | — | — | US | disclosed |
| US-20030100750-A1 | Process for solid supported synthesis of pyruvate-derived compounds | EDISON PHARMACEUTICALS, INC. | 2003-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100750-A1 | Process for solid supported synthesis of pyruvate-derived compounds | PC, PDK4, PDK1 | ALDH1A1 3046/4885HTT 2689/4885KDM4E 1736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.