Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 17/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 16/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | CRHBP | P24387 | 1/20 | 1.00 |
| ▸ | CRHR2 | Q13324 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 8/20 | 0.86 |
| ▸ | HTT | P42858 | 3/20 | 0.86 |
| ▸ | THRB | P10828 | 2/20 | 0.86 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.86 |
| ▸ | HPGD | P15428 | 4/20 | 0.78 |
| ▸ | USP2 | O75604 | 1/20 | 0.78 |
| ▸ | BLM | P54132 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057542 | 1.00 | MAPT (1.00) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL31026882 | 0.91 | MAPT (1.00) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL12548617 | 0.91 | MAPT (1.00) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL12548110 | 0.89 | MAPT (0.80) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL12548388 | 0.87 | MAPT (0.77) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL10490301 | 0.86 | ALDH1A1 (0.74) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL29394246 | 0.86 | MAPT (0.79) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL11327357 | 0.85 | MAPT (0.74) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL11327352 | 0.85 | MAPT (0.74) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL22299740 | 0.84 | MAPT (0.72) | MAPTALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030138374-A1 | Image diagnosis probe based on substituted azobenzene or analogue thereof for disease attributable to amyloid accumulation and composition for image diagnosis containing the same | BF RESEARCH INSTITUTE, INC. (JP) | 2003-07-24 | — | — | US | disclosed |
| EP-1266884-A1 | IMAGE DIAGNOSIS PROBE BASED ON SUBSTITUTED AZOBENZENE OR ANALOGUE THEREOF FOR DISEASE ATTRIBUTABLE TO AMYLOID ACCUMULATION AND COMPOSITION FOR IMAGE DIAGNOSIS CONTAINING THE SAME | BF Research Institute, Inc. (JP) | 2002-12-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030138374-A1 | Image diagnosis probe based on substituted azobenzene or analogue thereof for disease attributable to amyloid accumulation and composition for image diagnosis containing the same | APBA1, S100B, APP | MAPT 124/4885ALDH1A1 2139/4885KDM4E 3711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.