SCHEMBL11327352

SCHEMBL11327352

CCN(CC)c1ccc(/N=C/c2ccccc2O)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.74
ALDH1A1 P00352 10/20 0.74
MEN1 O00255 8/20 0.74
KMT2A Q03164 8/20 0.74
KDM4E B2RXH2 7/20 0.74
LMNA P02545 5/20 0.74
TDP1 Q9NUW8 2/20 0.74
CRHBP P24387 1/20 0.74
CRHR2 Q13324 1/20 0.74
GAA P10253 6/20 0.67
THRB P10828 4/20 0.67
MAPK1 P28482 3/20 0.67
SIRT2 Q8IXJ6 1/20 0.67
HTT P42858 3/20 0.64
NPSR1 Q6W5P4 1/20 0.64
L3MBTL1 Q9Y468 2/20 0.61
PTBP1 P26599 1/20 0.61
RAB9A P51151 2/20 0.59
HPGD P15428 2/20 0.59
USP2 O75604 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11327357 1.00 MAPT (0.74) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL7057542 0.85 MAPT (1.00) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL7057544 0.85 MAPT (1.00) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL31284246 0.83 SIRT2 (0.73) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL441694 0.83 SIRT2 (0.73) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL441693 0.83 SIRT2 (0.73) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL31026882 0.82 MAPT (1.00) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL12548617 0.82 MAPT (1.00) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL2494083 0.82 SIRT2 (1.00) MAPTKDM4ELMNAGAASIRT2
SCHEMBL2494084 0.82 SIRT2 (1.00) MAPTKDM4ELMNAGAASIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8758897-B2 Schiff base type color conversion layer, light absorbing layer, and filter ADEKA CORPORATION (JP) 2014-06-24 US disclosed
US-8758897-B2 Schiff base type color conversion layer, light absorbing layer, and filter ADEKA CORPORATION (JP) 2014-06-24 US disclosed
US-8568884-B2 Schiff base type compound and coloring material containing the same ADEKA CORPORATION (JP) 2013-10-29 US disclosed
US-8568884-B2 Schiff base type compound and coloring material containing the same ADEKA CORPORATION (JP) 2013-10-29 US disclosed
US-20130252024-A1 SCHIFF BASE TYPE COLOR CONVERSION LAYER, LIGHT ABSORBING LAYER, AND FILTER ADEKA CORPORATION (JP) 2013-09-26 US disclosed
US-20130252024-A1 SCHIFF BASE TYPE COLOR CONVERSION LAYER, LIGHT ABSORBING LAYER, AND FILTER ADEKA CORPORATION (JP) 2013-09-26 US disclosed
US-20110135958-A1 SCHIFF BASE TYPE COMPOUND AND COLORING MATERIAL CONTAINING THE SAME ADEKA CORPORATION (JP) 2011-06-09 US disclosed
US-20110135958-A1 SCHIFF BASE TYPE COMPOUND AND COLORING MATERIAL CONTAINING THE SAME ADEKA CORPORATION (JP) 2011-06-09 US disclosed
US-4258129-A IMPROVE GREEN SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US disclosed
US-4211839-A SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-07-08 US disclosed
US-4188212-A BEZNOTRIAZOLE FUJI PHOTO FILM CO., LTD. (JP) 1980-02-12 US disclosed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110135958-A1 SCHIFF BASE TYPE COMPOUND AND COLORING MATERIAL CONTAINING THE SAME ALDH1A2, ASIC1, IK MAPT 3058/4885ALDH1A1 12/4885MEN1 568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.