Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790696 | 0.81 | GABRA1 (0.41) | POLBMGAMGAASIMGAM2 | |
| SCHEMBL20226271 | 0.79 | CA12 (0.33) | HSD17B10POLBCYP3A4ALOX15GABRA1 | |
| SCHEMBL11639066 | 0.75 | KDM4E (0.37) | HSD17B10POLBGAATLR4 | |
| SCHEMBL20226270 | 0.75 | GABRA1 (0.44) | HSD17B10POLBMGAMGAASI | |
| SCHEMBL28719947 | 0.74 | TLR4 (0.33) | TLR4 | |
| SCHEMBL1396137 | 0.73 | PTPN1 (0.31) | — | |
| SCHEMBL9253029 | 0.73 | ALDH1A1 (0.36) | POLBGAACYP3A4ALOX15GABRA1 | |
| SCHEMBL11602955 | 0.69 | GABRA1 (0.47) | GABRA1GABRB2TLR4 | |
| SCHEMBL21840790 | 0.68 | TLR4 (0.36) | HSD17B10CYP3A4GABRA1GABRB2CA12 | |
| SCHEMBL20226269 | 0.68 | HTT (0.36) | HSD17B10MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397427-A1 | THERMOPLASTIC RESINS IN CONTACT WITH METALS OR METAL SALTS STABILIZED BY BLENDS OF DITHIOCARBAMATES AND METAL DEACTIVATORS | Crompton Corporation (US) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002092685-A1 | THERMOPLASTIC RESINS IN CONTACT WITH METALS OR METAL SALTS STABILIZED BY BLENDS OF DITHIOCARBAMATES AND METAL DEACTIVATORS | CROMPTON CORPORATION (US) | 2002-11-21 | — | — | WO | disclosed |