Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20226270 | 0.85 | GABRA1 (0.44) | CYP3A4ALOX15MAPTGABRA1GABRB2 | |
| SCHEMBL29370071 | 0.82 | GABRA1 (0.44) | ALDH1A1PPARGPPARDPPARACYP3A4 | |
| SCHEMBL2462713 | 0.80 | ALDH1A1 (0.39) | ALDH1A1PPARGPPARDPPARACYP3A4 | |
| SCHEMBL5082696 | 0.80 | FFAR4 (0.40) | ALDH1A1PPARGPPARDPPARACYP3A4 | |
| SCHEMBL11602955 | 0.79 | GABRA1 (0.47) | ALDH1A1SMN1; SMN2TP53TSHRMAPT | |
| SCHEMBL1473043 | 0.79 | ADRA2A (0.35) | ALDH1A1PPARGPPARDPPARACYP3A4 | |
| SCHEMBL20956961 | 0.78 | XDH (0.40) | ALDH1A1PPARGPPARDPPARACYP3A4 | |
| SCHEMBL9618034 | 0.77 | POLB (0.51) | ALDH1A1CYP3A4SMN1; SMN2ALOX15KDM4E | |
| SCHEMBL20226269 | 0.77 | HTT (0.36) | ALDH1A1CYP3A4SMN1; SMN2ALOX15MEN1 | |
| SCHEMBL11586876 | 0.77 | CNR2 (0.52) | ALDH1A1PPARGPPARDPPARACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4227912-A | — | — | None | — | — | JP | disclosed |
| EP-0457732-B1 | Curable compositions | CIBA GEIGY AG (CH) | 1995-03-01 | — | — | EP | disclosed |
| US-5183869-A | Bismaleimides, 2-6-dialkyl-4-allylphenols or 2,6-dialkyl-4-allylphenol allyl ethers; crosslinking | CIBA-GEIGY CORPORATION (US) | 1993-02-02 | — | — | US | disclosed |
| JP-H04227912-A | NEW HARDENABLE COMPOSITION | CIBA GEIGY AG | 1992-08-18 | — | — | JP | disclosed |
| EP-0457732-A1 | Curable compositions | CIBA-GEIGY AG (CH) | 1991-11-21 | — | — | EP | disclosed |