Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3765002 | 0.83 | SNCA (0.46) | ALDH1A1SNCA | |
| SCHEMBL18322761 | 0.81 | SNCA (0.43) | BCHEACHESNCA | |
| SCHEMBL3398769 | 0.81 | CA2 (0.46) | SNCA | |
| SCHEMBL27829874 | 0.81 | SNCA (0.42) | ALDH1A1SNCA | |
| SCHEMBL29555802 | 0.80 | EGFR (0.50) | — | |
| SCHEMBL2061458 | 0.80 | ALDH1A1 (0.49) | BCHEACHEALDH1A1 | |
| SCHEMBL3149580 | 0.80 | NR1D1 (0.47) | ALDH1A1 | |
| SCHEMBL20512380 | 0.79 | BCHE (0.54) | BCHEACHEALDH1A1SNCA | |
| SCHEMBL27848279 | 0.79 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL19717778 | 0.79 | ALDH1A1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762180-B1 | Substituted indolines which inhibit receptor tyrosine kinases | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2004-07-13 | — | — | US | disclosed |