Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7058583 | 1.00 | CYP1A2 (0.43) | CYP1A2TSHRCYP2A6ALDH1A1MAPT | |
| SCHEMBL5589346 | 0.81 | CTH (0.36) | CYP1A2TSHRCYP2A6ALDH1A1MAPT | |
| SCHEMBL5589354 | 0.81 | CTH (0.36) | CYP1A2TSHRCYP2A6ALDH1A1MAPT | |
| SCHEMBL5587761 | 0.79 | CTH (0.35) | CYP1A2TSHRCYP2A6ALDH1A1MAPT | |
| SCHEMBL5693787 | 0.79 | CTH (0.35) | CYP1A2TSHRCYP2A6ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7174410 | 0.78 | NR4A1 (0.36) | CYP1A2TSHRALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7177279 | 0.78 | NR4A1 (0.36) | CYP1A2TSHRALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7179444 | 0.78 | NR4A1 (0.36) | CYP1A2TSHRALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7171706 | 0.78 | NR4A1 (0.36) | CYP1A2ALDH1A1MAPTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7176751 | 0.78 | NR4A1 (0.36) | CYP1A2ALDH1A1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670434-B2 | Transition metal complex | SOLVAY POLYOLEFINS EUROPE-BELGIUM (SOCIETE ANONYME) (BE) | 2003-12-30 | — | — | US | disclosed |
| US-20030018147-A1 | Catalytic complexes and their use for polymerizing alpha-olefins | SOLVAY POLYOLEFINS EUROPE-BELGIUM (BE) | 2003-01-23 | — | — | US | disclosed |
| EP-1260515-A1 | Catalytic complexes and their use for polymerizing alpha-olefins | SOLVAY POLYOLEFINS EUROPE - BELGIUM (Société Anonyme) (BE) | 2002-11-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018147-A1 | Catalytic complexes and their use for polymerizing alpha-olefins | POLA1, ETFB, POLB | CYP1A2 251/4885TSHR 3576/4885CYP2A6 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.