SCHEMBL7058599

SCHEMBL7058599

O=S(=O)(O)C(Oc1cccnn1)S(=O)(=O)O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
P2RX7 Q99572 1/20 0.33
NAPRT Q6XQN6 1/20 0.32
CCR2 P41597 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL129824 0.83 CTDSP1 (0.32) CYP1A2P2RX7NAPRTCCR2CTDSP1
SCHEMBL31067927 0.76 P2RX7 (0.35) CYP1A2P2RX7NAPRTCCR2CTDSP1
SCHEMBL997656 0.71 P2RX7 (0.36) CYP1A2P2RX7NAPRTCCR2CTDSP1
SCHEMBL31092383 0.71 GRIN1 (0.40) CYP1A2
SCHEMBL2424317 0.71 GABRA1 (0.42) CYP1A2CTDSP1
SCHEMBL16235549 0.71 GRIN1 (0.40) CYP1A2
SCHEMBL21618135 0.70 P2RX7 (0.34) CYP1A2P2RX7CTDSP1
SCHEMBL28443035 0.70 P2RX7 (0.35) CYP1A2P2RX7NAPRTCCR2CTDSP1
SCHEMBL907708 0.70 CYP1A2 (0.45) CYP1A2P2RX7CTDSP1
SCHEMBL12878804 0.70 CTDSP1 (0.36) CYP1A2P2RX7CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6800631-B2 STABLE TO BE ADMINISTERED VIA THE DRINKING WATER OF ANIMALS; SHELF-LIFE; PALATABLE ANTIMICROBIAL DRUG CONCENTRATE STROBEL MICHAEL A (US) 2004-10-05 US disclosed
US-20020183287-A1 Method of producing a concentrate comprising a sulfonamide in solution, a 2,4-diaminopyrimidine in stable suspension within said solution STROBEL MICHAEL A (US) 2002-12-05 US disclosed
US-6410543-B1 MICROBIOCIDES; MIXTURE OF ANTIOXIDANT, SWEETENER AND FLAVOR PHARMACEUTICAL SOLUTIONS, INC. 2002-06-25 US disclosed
US-6211185-B1 ADMINISTERING ORALLY WITH DRINKING WATER VETERINARY PHARMACY CORPORATION 2001-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020183287-A1 Method of producing a concentrate comprising a sulfonamide in solution, a 2,4-diaminopyrimidine in stable suspension within said solution DPYD, DUS2, DHPS CYP1A2 1382/4885P2RX7 284/4885NAPRT 539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.