Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059006 | 0.94 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL7055814 | 0.93 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL7059080 | 0.91 | MCHR1 (0.43) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL7058462 | 0.91 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL7060766 | 0.90 | MCHR1 (0.40) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL7055517 | 0.90 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL7056991 | 0.90 | MEN1 (0.42) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL7058602 | 0.89 | MEN1 (0.49) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL7057769 | 0.88 | EGFR (0.39) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL6052303 | 0.88 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | claimed |