Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA7 | P43166 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278222 | 0.86 | CYP3A4 (0.40) | CYP3A4ALDH1A1TSHRTYMSCA1 | |
| SCHEMBL10778120 | 0.81 | AKR1C4 (0.46) | CYP3A4ALDH1A1TSHRTYMSCA1 | |
| SCHEMBL11225804 | 0.80 | ALDH1A1 (0.42) | CYP3A4ALDH1A1TSHRTYMSCA1 | |
| SCHEMBL6541546 | 0.79 | TYMS (0.51) | CYP3A4ALDH1A1TSHRTYMSCA1 | |
| SCHEMBL9401859 | 0.78 | TYMS (0.51) | CYP3A4ALDH1A1TSHRTYMSCA1 | |
| SCHEMBL11410011 | 0.76 | AKR1C2 (0.44) | ALDH1A1TSHRTYMSCA1CA12 | |
| SCHEMBL2884593 | 0.76 | ALDH1A1 (0.45) | CYP3A4ALDH1A1TSHRCA1CA12 | |
| SCHEMBL540750 | 0.76 | TYMS (0.50) | ALDH1A1TSHRTYMSCA1CA12 | |
| SCHEMBL11788566 | 0.76 | ALDH1A1 (0.48) | ALDH1A1TSHRTYMSCA1CA12 | |
| SCHEMBL5671377 | 0.75 | TYMS (0.51) | CYP3A4ALDH1A1TSHRTYMSCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114736213-B | Preparation method of carboxyl-tetrachloro-fluorescein | 合肥华纳生物医药科技有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-114736213-A | Preparation method of carboxyl-tetrachloro-fluorescein | 合肥华纳生物医药科技有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-114736213-A | Preparation method of carboxyl-tetrachloro-fluorescein | 合肥华纳生物医药科技有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114736213-A | Preparation method of carboxyl-tetrachloro-fluorescein | 合肥华纳生物医药科技有限公司 | 2022-07-12 | — | — | CN | disclosed |
| US-9551029-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2017-01-24 | — | — | US | disclosed |
| US-20160122813-A1 | Methods And Kits Using Extended Rhodamine Dyes | THE PERKIN-ELMER CORPORATION | 2016-05-05 | — | — | US | disclosed |
| US-9309561-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2016-04-12 | — | — | US | disclosed |
| US-20140171336-A1 | Methods and Kits Using Extended Rhodamine Dyes | Life Technologies Corporation (US) | 2014-06-19 | — | — | US | disclosed |
| EP-1034221-B1 | DIBENZORHODAMINE DYES USEFUL AS FLUORESCENT LABELLING AGENTS | LIFE TECHNOLOGIES CORP (US) | 2014-05-14 | — | — | EP | disclosed |
| US-8628975-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2014-01-14 | — | — | US | disclosed |
| US-20120135885-A1 | Methods and Kits Using Extended Rhodamine Dyes | Life Technologies Corporation (US) | 2012-05-31 | — | — | US | disclosed |
| US-6221606-B1 | ENERGY TRANSFER DYE COMPRISING A DONOR DYE WHICH ABSORBS IGHT AND EMITS EXITATION ENERGY, AN ACCEPTOR DYE THE ABSORBS THE EXCITATION ENERGY AND FLUORESCES IN RESPONSE, AND A LINKER LINKING THE TWO DYES, AT LEAST ONE IS A DIBENZORHODAMINE DYE | THE PERKIN-ELMER CORPORATION | 2001-04-24 | — | — | US | disclosed |
| WO-2000075236-A1 | EXTENDED RHODAMINE COMPOUNDS USEFUL AS FLUORESCENT LABELS | PE CORPORATION (NY) (US) | 2000-12-14 | — | — | WO | disclosed |
| EP-1034221-A1 | DIBENZORHODAMINE DYES USEFUL AS FLUORESCENT LABELLING AGENTS | THE PERKIN-ELMER CORPORATION (US) | 2000-09-13 | — | — | EP | disclosed |
| US-6111116-A | FLUORESCENT LABELING REAGENTS | THE PERKIN-ELMER CORPORATION (US) | 2000-08-29 | — | — | US | disclosed |
| US-6051719-A | FLUORESCENT LABELING REAGENTS | THE PERKIN-ELMER CORPORATION (US) | 2000-04-18 | — | — | US | disclosed |
| US-6025505-A | FLUORESCENT LABELING PROBES FOR IMMUNOASSAYS, DNA SEQUENCING, DETECTING PRODUCTS OF POLYMERASE CHAIN REACTIONS | THE PERKIN-ELMER CORPORATION (US) | 2000-02-15 | — | — | US | disclosed |
| US-6017712-A | NUCLEOTIDE LABELED WITH XANTHENE DYE HAVING NARROWER EMISSION SPECTRUM AND WITH ABSORPTION SPECTRUM SHIFTED TO THE RED; FOR MOLECULAR PROBES AND IN NUCLEIC ACID SEQUENCING | APPLIED BIOSYSTEMS, LLC | 2000-01-25 | — | — | US | disclosed |
| US-5936087-A | FLUORESCENT LABELS; DNA SEQUENCING | THE PERKIN-ELMER CORPORATION (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1999027020-A1 | DIBENZORHODAMINE DYES USEFUL AS FLOURESCENT LABELLING AGENTS | THE PERKIN-ELMER CORPORATION (US) | 1999-06-03 | — | — | WO | disclosed |