SCHEMBL2884593

SCHEMBL2884593

O=C(O)c1cc(Cl)c2c(c1Cl)C(=O)OC2=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
TSHR P16473 4/20 0.45
CYP3A4 P08684 1/20 0.43
AKR1C2 P52895 2/20 0.40
AKR1C1 Q04828 2/20 0.40
AKR1C4 P17516 1/20 0.40
AKR1C3 P42330 1/20 0.40
KDM4E B2RXH2 3/20 0.40
HPGD P15428 2/20 0.40
HSD17B10 Q99714 2/20 0.40
HTT P42858 2/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.40
KMT2A Q03164 1/20 0.40
CASP1 P29466 2/20 0.39
GPR35 Q9HC97 2/20 0.39
POLB P06746 2/20 0.39
USP2 O75604 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705878 0.76 CYP3A4 (0.46) ALDH1A1TSHRCYP3A4AKR1C2AKR1C1
SCHEMBL14389310 0.76 NPC1 (0.44) ALDH1A1TSHRKDM4EHPGDHSD17B10
SCHEMBL13447195 0.76 TSHR (0.36) ALDH1A1TSHRKDM4E
SCHEMBL855290 0.76 TSHR (0.56) ALDH1A1TSHRCYP3A4HPGDHSD17B10
SCHEMBL9401940 0.75 TYMS (0.46) ALDH1A1TSHRKDM4EHPGDHSD17B10
SCHEMBL12992919 0.74 TRPA1 (0.36) ALDH1A1TSHRSMN1; SMN2
SCHEMBL6541546 0.73 TYMS (0.51) ALDH1A1TSHRCYP3A4KDM4EMEN1
SCHEMBL10605868 0.73 CYP3A4 (0.42) ALDH1A1TSHRCYP3A4AKR1C2AKR1C1
SCHEMBL4939317 0.72 ALDH1A1 (0.46) ALDH1A1TSHRMEN1KMT2A
SCHEMBL10778120 0.72 AKR1C4 (0.46) ALDH1A1TSHRCYP3A4AKR1C2AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119119374-A UV-cured high-temperature-resistant resin for thermal runaway protection material and application 武汉长盈鑫科技有限公司 2024-12-13 CN claimed
CN-116606271-B Synthesis method of 3, 6-dichloro trimellitic anhydride 北京百力格生物科技有限公司 2023-09-29 CN claimed
CN-116606271-A Synthesis method of 3, 6-dichloro trimellitic anhydride 北京百力格生物科技有限公司 2023-08-18 CN claimed
CN-114645445-A Cool deodorizing fabric and preparation method thereof 牛群 2022-06-21 CN claimed
CN-112126150-A Recyclable POE vitrimer elastomer, foaming material, and preparation methods and applications thereof 上海交通大学 2020-12-25 CN claimed
CN-120202243-A Thermosetting resin composition, cured film, substrate, and electronic component 捷恩智株式会社 2025-06-24 CN disclosed
CN-119119374-A UV-cured high-temperature-resistant resin for thermal runaway protection material and application 武汉长盈鑫科技有限公司 2024-12-13 CN disclosed
CN-116606271-B Synthesis method of 3, 6-dichloro trimellitic anhydride 北京百力格生物科技有限公司 2023-09-29 CN disclosed
CN-116606271-B Synthesis method of 3, 6-dichloro trimellitic anhydride 北京百力格生物科技有限公司 2023-09-29 CN disclosed
CN-116606271-B Synthesis method of 3, 6-dichloro trimellitic anhydride 北京百力格生物科技有限公司 2023-09-29 CN disclosed
CN-116606271-A Synthesis method of 3, 6-dichloro trimellitic anhydride 北京百力格生物科技有限公司 2023-08-18 CN disclosed
CN-116606271-A Synthesis method of 3, 6-dichloro trimellitic anhydride 北京百力格生物科技有限公司 2023-08-18 CN disclosed
US-5800996-A Energy transfer dyes with enchanced fluorescence THE PERKIN ELMER CORPORATION (US) 1998-09-01 US disclosed
WO-1997049769-A1 4,7-DICHLORORHODAMINE DYES THE PERKIN-ELMER CORPORATION (US) 1997-12-31 WO disclosed
EP-0805190-A2 Energy transfer dyes with enhanced fluorescence PERKIN-ELMER CORPORATION (US) 1997-11-05 EP disclosed
US-4652531-A Fluorescent protein binding assays with unsymmetrical fluorescein derivatives SYNTEX (U.S.A.) INC. (US) 1987-03-24 US disclosed
EP-0050684-B1 NOVEL ETHER SUBSTITUTED FLUORESCEIN COMPOUNDS AS FLUORESCERS AND QUENCHERS SYVA COMPANY (US) 1986-01-22 EP disclosed
US-4439356-A XANTHENES, IMMUNOASSAY SYVA COMPANY (US) 1984-03-27 US disclosed
EP-0050684-A1 Novel ether substituted fluorescein compounds as fluorescers and quenchers SYVA COMPANY (US) 1982-05-05 EP disclosed
US-4318846-A RADIOIMMUNOASSAY SYVA COMPANY (US) 1982-03-09 US disclosed