Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080352 | 0.78 | MAPK1 (0.38) | ALOX5ESR2ESR1TDP1CA12 | |
| SCHEMBL2958548 | 0.76 | ALDH1A1 (0.45) | BCL2L1MMP3ALOX5TDP1CA12 | |
| SCHEMBL2448169 | 0.76 | ALDH1A1 (0.45) | BCL2L1MMP3ALOX5TDP1CA12 | |
| SCHEMBL5047733 | 0.75 | ALDH1A1 (0.47) | BCL2L1MMP3TDP1MEN1KMT2A | |
| SCHEMBL781962 | 0.73 | LMNA (0.38) | TDP1MEN1KMT2ANTSR1ALDH1A1 | |
| SCHEMBL2922472 | 0.73 | ALDH1A1 (0.35) | ALOX5ALDH1A1NPC1 | |
| SCHEMBL9316232 | 0.73 | HSD17B10 (0.48) | TDP1GLAMEN1KMT2AALDH1A1 | |
| SCHEMBL358614 | 0.73 | CYP1A2 (0.48) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL15475160 | 0.71 | SMN1; SMN2 (0.38) | ESR2ESR1MEN1KMT2AALDH1A1 | |
| SCHEMBL9057820 | 0.70 | WDR5 (0.57) | KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | claimed |
| WO-2021006267-A1 | SALT OF PYRAZOLE DERIVATIVE AND PREPARATION OF PYRAZOLE DERIVATIVE | グリーン・テック株式会社 | 2021-01-14 | — | — | WO | disclosed |
| WO-2020235582-A1 | PREVENTIVE AND/OR THERAPEUTIC AGENT FOR MOTOR NEURON DISEASE | グリーン・テック株式会社 (JP) | 2020-11-26 | — | — | WO | disclosed |
| EP-3323816-A1 | NOVEL PYRAZOLE DERIVATIVE | Green Tech Co., Ltd. (JP) | 2018-05-23 | — | — | EP | disclosed |
| US-9399635-B2 | Pyrazole derivative | GREEN TECH CO., LTD. (JP) | 2016-07-26 | — | — | US | disclosed |
| US-20140088029-A1 | NOVEL PYRAZOLE DERIVATIVE | PHARMA EIGHT CO., LTD. (JP) | 2014-03-27 | — | — | US | disclosed |
| EP-2698368-A1 | NOVEL PYRAZOLE DERIVATIVE | Pharma Eight Co. Ltd (JP) | 2014-02-19 | — | — | EP | disclosed |
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |
| EP-0508424-B1 | Method for preparing sulfones | SANKO KAIHATSU KAGAKU KENK (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5371105-A | Agrochemically active substrance mixed with crystal growth inhibitor | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |
| EP-0357559-B1 | Aqueous formulations and their use | HOECHST AG (DE) | 1994-10-19 | — | — | EP | disclosed |
| US-5248828-A | Method for preparing sulfones | SANKO KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-09-28 | — | — | US | disclosed |
| US-5235084-A | METHOD FOR PREPARING SULFONES | SANKO KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0508424-A2 | Method for preparing sulfones | Sanko Kaihatsu Kagaku Kenkyusho (JP) | 1992-10-14 | — | — | EP | disclosed |
| EP-0357559-A2 | Aqueous formulations and their use | AgrEvo UK Limited (GB) | 1990-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088029-A1 | NOVEL PYRAZOLE DERIVATIVE | PSEN2, MAPT, PSEN1 | BCL2L1 2355/4885MMP3 2979/4885ALOX5 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.