Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 9/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.45 |
| ▸ | MAP2 | P11137 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CHUK | O15111 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3236462 | 0.88 | ACHE (0.47) | ALDH1A1PARP1NPC1RAB9ANR4A2 | |
| SCHEMBL28739198 | 0.84 | KDM5A (0.48) | KDM5AKDM5BADORA3CHUKPARP1 | |
| SCHEMBL29706650 | 0.84 | KDM5A (0.48) | KDM5AKDM5BADORA3CHUKPARP1 | |
| SCHEMBL15173538 | 0.80 | NR4A2 (0.63) | KDM5AKDM5BKDM4ECHUKALDH1A1 | |
| SCHEMBL16344722 | 0.79 | KDM5A (0.43) | KDM5AKDM5BMAP2ADORA3KDM4E | |
| SCHEMBL25942231 | 0.78 | KDM5A (0.68) | KDM5AKDM5BKDM4ESMN1; SMN2GABRP | |
| SCHEMBL1559343 | 0.77 | NR4A2 (0.63) | KDM4ESMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL29955041 | 0.72 | CHUK (0.44) | KDM5AKDM5BADORA3KDM4ESMN1; SMN2 | |
| SCHEMBL1569016 | 0.72 | MAP2 (0.52) | KDM5AKDM5BMAP2ADORA3KDM4E | |
| SCHEMBL6388405 | 0.72 | AHR (0.52) | KDM5AADORA3KDM4ESMN1; SMN2CHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160075703-A1 | SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES | VIIV HEALTHCARE UK (NO. 4) LIMITED (GB) | 2016-03-17 | — | — | US | disclosed |
| US-20030181463-A1 | Antiviral azaindole derivatives | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2003-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075703-A1 | SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES | ITPA, IDO1, IDO2 | KDM5A 173/4885KDM5B 211/4885MAP2 3556/4885 |
| US-20030181463-A1 | Antiviral azaindole derivatives | ZC3HAV1, MAVS, AZI2 | KDM5A 288/4885KDM5B 377/4885MAP2 1549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.