Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 5/20 | 0.50 |
| ▸ | DRD3 | P35462 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6195674 | 0.91 | MAPK1 (0.53) | KMT2ADRD2DRD3MAPK1DRD4 | |
| SCHEMBL6194286 | 0.87 | KDM4E (0.49) | KMT2ADRD2DRD3MAPK1DRD4 | |
| SCHEMBL6195013 | 0.84 | MCHR1 (0.49) | KMT2AMEN1DRD2DRD3ALDH1A1 | |
| SCHEMBL6192405 | 0.82 | MAPK1 (0.47) | KMT2AMEN1DRD2DRD3MAPK1 | |
| SCHEMBL6196310 | 0.80 | DRD2 (0.45) | DRD2DRD3MAPK1HTR1AADRA1D | |
| SCHEMBL6192022 | 0.79 | NPC1 (0.67) | DRD2DRD3MAPK1DRD4KDM4E | |
| SCHEMBL11719727 | 0.77 | DRD2 (0.56) | KMT2AMEN1DRD2DRD3MAPK1 | |
| SCHEMBL10819392 | 0.76 | DRD2 (0.58) | KMT2AMEN1DRD2DRD3MAPK1 | |
| SCHEMBL14044704 | 0.76 | MCHR1 (0.48) | KMT2AMEN1DRD2DRD3ALDH1A1 | |
| SCHEMBL12962208 | 0.75 | NPC1 (0.61) | DRD2DRD3MAPK1DRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030181446-A1 | Novel N-acylated heterocycles | RECORDATI S.A. | 2003-09-25 | — | — | US | disclosed |
| US-20030162777-A1 | Novel N-acylated heterocycles | RECORDATI S.A. | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162777-A1 | Novel N-acylated heterocycles | HTR1A, HTR1D, HTR1E | KMT2A 2287/4885MEN1 1822/4885DRD2 163/4885 |
| US-20030181446-A1 | Novel N-acylated heterocycles | HTR1A, HTR1E, HTR2C | KMT2A 3319/4885MEN1 2190/4885DRD2 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.