Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.39 |
| ▸ | ITGAV | P06756 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1072536 | 0.94 | ITGB3 (0.39) | ITGB3ITGA2BITGAV | |
| SCHEMBL8311626 | 0.91 | ALDH1A1 (0.36) | ITGB3ITGA2BITGAV | |
| SCHEMBL7059871 | 0.88 | ITGB3 (0.38) | ITGB3ITGA2BITGAV | |
| SCHEMBL7059299 | 0.87 | ITGB3 (0.35) | ITGB3ITGA2B | |
| SCHEMBL1070617 | 0.85 | ITGB3 (0.36) | ITGB3ITGA2BITGAV | |
| SCHEMBL1071119 | 0.84 | ITGB3 (0.41) | ITGB3ITGA2BITGAV | |
| SCHEMBL1071022 | 0.81 | ITGB3 (0.39) | ITGB3ITGA2BITGAV | |
| SCHEMBL1067956 | 0.81 | ITGB3 (0.35) | ITGB3ITGA2BITGAV | |
| SCHEMBL1071021 | 0.81 | ITGAV (0.43) | ITGB3ITGA2BITGAV | |
| SCHEMBL5779990 | 0.80 | ITGB3 (0.41) | ITGB3ITGA2BITGAVTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307226-A2 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | Bristol-Myers Squibb Pharma Company (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2001097848-A2 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-12-27 | — | — | WO | disclosed |